Description
Specifications Table
Product Name – Sodium perchlorate HiPerSolv CHROMANORM® for HPLC
Quantity/Pack Size – 250 g
Form – Crystalline powder
Grade – HiPerSolv CHROMANORM® (HPLC-grade)
Application – High-performance liquid chromatography (HPLC), ion-pairing reagent, analytical standards
Product Overview
Sodium perchlorate HiPerSolv CHROMANORM® is a high-purity, chromatographic-grade reagent engineered for demanding HPLC applications where trace metal contamination and baseline stability are critical. This crystalline powder undergoes rigorous purification to meet the stringent CHROMANORM® standards, ensuring minimal interference in UV, RI, or MS detection. Its low hygroscopicity and high solubility in polar solvents make it an ideal ion-pairing agent for reverse-phase separations, particularly in pharmaceutical, environmental, and biochemical analyses. The reagent’s consistent lot-to-lot performance is validated through comprehensive quality control, including ICP-MS testing for metal impurities (typically <1 ppm for most transition metals) and HPLC suitability assessments. Unlike technical-grade alternatives, this product is free from stabilizers or additives that could compromise chromatographic integrity. Its neutral pH in solution (6.0–8.0 at 5% w/v) further reduces the risk of column degradation or analyte instability. For laboratories prioritizing reproducibility, this sodium perchlorate variant delivers unmatched purity, with residual solvent levels compliant with ICH Q3C guidelines. Store under inert gas for prolonged shelf life, though the sealed packaging maintains stability for up to 24 months under standard conditions.
FAQs
1. What is the maximum allowable metal impurity level in this sodium perchlorate grade?
This HiPerSolv CHROMANORM® grade is tested via ICP-MS, with most transition metals (e.g., Fe, Cu, Ni) maintained below 1 ppm and alkali/alkaline earth metals under 5 ppm to prevent column or detector interference.
2. Can this reagent be used with LC-MS systems without ion suppression?
The low-metal profile and absence of volatile additives minimize ion suppression, but we recommend evaluating matrix effects with your specific analyte and mobile phase, as perchlorate itself may impact ionization efficiency in ESI sources.
3. How does this compare to ACS-grade sodium perchlorate for HPLC?
ACS-grade products lack the rigorous chromatographic validation of CHROMANORM®; they may contain higher levels of UV-absorbing impurities or metals, leading to elevated baselines or ghost peaks in gradient separations.
4. What’s the recommended storage condition to prevent moisture absorption?
While the primary packaging includes a desiccant, for opened containers, store under nitrogen or argon in a desiccator at 15–25°C to maintain the anhydrous form and prevent clumping.
5. Is this product compatible with stainless-steel HPLC systems?
Yes, but prolonged exposure to perchlorate solutions (>100 ppm) may accelerate corrosion in stainless-steel components; rinse the system with water or 20% isopropanol post-use to mitigate this effect.
