Description
Specifications Table
Product Name – Succinyl chloride, ca. 95%, AcroSeal®
Quantity/Pack Size – 100ML
Form – Liquid
Grade – Synthesis Grade
Application – Acylation reactions, peptide synthesis, organic derivatization
Product Overview
Succinyl chloride (C₄H₄Cl₂O₂) is a highly reactive acyl chloride derivative of succinic acid, supplied at 95% minimum purity in an AcroSeal® bottle to prevent moisture-induced hydrolysis. Its bifunctional structure makes it a versatile reagent for introducing succinyl groups in organic synthesis, particularly in acylation reactions where it forms stable amide or ester bonds. The liquid form ensures easy handling and precise dosing, while the synthesis-grade purity minimizes side reactions, making it suitable for demanding applications like peptide chain elongation or protective group chemistry. The AcroSeal® packaging features a tamper-evident seal and inert atmosphere, preserving reactivity during storage. Compatible with anhydrous solvents like dichloromethane or THF, it requires standard acyl chloride handling precautions—storage under nitrogen or argon is recommended to maintain stability. This reagent is a critical building block for synthesizing succinic acid derivatives, polymers, or bioactive compounds where succinyl linkages are required.
FAQs
1. What is the shelf life of Succinyl chloride in AcroSeal® packaging?
The product remains stable for 12 months from the date of manufacture when stored unopened at 2–8°C under inert gas. Always check the label for the exact expiry date.
2. Can this reagent be used directly in aqueous solutions?
No, succinyl chloride hydrolyzes rapidly in water, forming succinic acid and HCl. Use anhydrous conditions and compatible solvents like DCM or acetone for reactions.
3. What are the key safety precautions for handling this chemical?
Wear nitrile gloves, safety goggles, and work in a fume hood due to its corrosive and lachrymatory nature. Avoid inhalation of vapors and ensure proper ventilation.
4. Is this suitable for large-scale synthesis, or only lab-scale?
The 100ML pack is optimized for lab-scale applications. For bulk requirements, consider custom packaging or higher-volume alternatives like 500ML or 1L bottles.
5. How does the AcroSeal® packaging improve stability compared to standard bottles?
AcroSeal® uses a multi-layer barrier with a resealable PTFE-lined cap and inert gas flush, reducing moisture ingress and oxidation, which significantly extends shelf life versus conventional packaging.
