Description
Specifications Table
| Product Name | tert-Butylchlorodiphenylsilane, 98%, AcroSeal® |
|---|---|
| Pack Size | 100ML |
| Form | Liquid |
| Grade | 98% |
| Application | Protecting group in organic synthesis |
Product Description
When precision matters in your lab work, tert-butylchlorodiphenylsilane stands out as a reliable choice for protecting alcohols and phenols during synthesis. This high-purity reagent, available in a convenient 100ml AcroSeal® package, ensures stability and consistency in your experiments. Whether you’re a student working on a research project or a professional chemist developing new compounds, this silylating agent offers excellent selectivity and ease of use.
The AcroSeal® packaging from Thermofisher guarantees freshness and prevents contamination, making it ideal for sensitive applications. Many researchers prefer this specific formulation because it provides cleaner reactions with fewer side products compared to other protecting groups. The 98% purity level meets the stringent requirements of advanced organic chemistry, ensuring reproducible results every time.
For those looking to buy tert-butylchlorodiphenylsilane online, eqipped offers a seamless purchasing experience with authentic Thermofisher products. Our platform connects you with genuine lab supplies that meet international quality standards, so you can focus on your work without worrying about supply chain issues.
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In practical lab settings, this compound finds extensive use in the protection of hydroxyl groups during multi-step organic syntheses. The bulky tert-butyldiphenylsilyl (TBDPS) group it forms is particularly useful when you need steric hindrance to prevent unwanted reactions at the protected site. This makes it invaluable in complex molecule construction where selective protection is crucial.
The 100ml pack size offers an optimal balance between quantity and shelf life, perfect for research labs with moderate usage patterns. Unlike smaller packages that might require frequent reordering, this size reduces storage concerns while maintaining freshness. The liquid form allows for easy handling and precise measurement, whether you’re working with microliter quantities or larger scale reactions.
When considering where to buy tert-butylchlorodiphenylsilane, it’s important to choose suppliers who maintain proper storage conditions. eqipped ensures that all chemical products are stored according to manufacturer specifications, preserving their integrity until they reach your lab. This attention to detail in the supply chain translates to better experimental outcomes for you.
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The versatility of this compound extends beyond standard protecting group chemistry. Advanced users often employ it in the synthesis of pharmaceutical intermediates, natural product derivatives, and complex organic molecules. Its stability under a wide range of reaction conditions makes it a favorite among organic chemists who need reliable performance in diverse synthetic routes.
For educational institutions, this product serves as an excellent teaching tool for demonstrating protection-deprotection strategies in organic chemistry courses. The clear reaction mechanisms and predictable behavior make it ideal for classroom demonstrations and student lab work. Many university chemistry departments include this reagent in their standard inventory for both teaching and research purposes.
When you buy tert-butylchlorodiphenylsilane 100ml from eqipped, you’re not just purchasing a chemical you’re investing in the success of your experiments. Our commitment to providing authentic, high-quality lab supplies means you can trust that what arrives at your door matches exactly what you ordered, with all the performance characteristics you expect from a Thermofisher product.
FAQs
What is the primary use of tert-butylchlorodiphenylsilane in organic synthesis?
It’s primarily used as a protecting group for alcohols and phenols, forming the bulky TBDPS ether that provides excellent steric protection during multi-step syntheses.
How should I store tert-butylchlorodiphenylsilane to maintain its purity?
Store in a cool, dry place under inert atmosphere (nitrogen or argon) in its original AcroSeal® packaging. Keep away from moisture and direct sunlight.
What safety precautions should I take when handling this compound?
Always work in a well-ventilated fume hood, wear nitrile gloves, safety goggles, and a lab coat. Avoid inhalation and skin contact as it can cause irritation.
Can I use this for large-scale synthesis, or is it only suitable for small-scale reactions?
While the 100ml pack is ideal for lab-scale work, the same chemistry can be scaled up. For industrial quantities, you might need to source larger packaging options.
What’s the typical deprotection method for TBDPS groups?
Common deprotection methods include treatment with fluoride sources like TBAF or HF-pyridine, or acidic conditions using HCl or TFA depending on the substrate.
