Description
Specifications Table
| Product Name | Tetrabutylammonium Hydroxide |
|---|---|
| Catalog Number | 1.94956.0121 |
| Pack Size | 100 ml |
| Form | Liquid (40% w/v in water) |
| Grade | For synthesis |
| Application | Phase-transfer catalyst, organic synthesis, chromatography |
Product Description
Tetrabutylammonium hydroxide (TBAH) is a quaternary ammonium compound widely used in organic synthesis as a phase-transfer catalyst. This high-purity solution from Merck (catalog number 1.94956.0121) is supplied as a 40% aqueous solution, making it convenient for laboratory applications where precise dosing is required.
In research settings, TBAH serves as a strong base in organic reactions, particularly in the deprotonation of weakly acidic compounds. Its solubility in both organic and aqueous phases makes it ideal for phase-transfer catalysis, enabling reactions between immiscible solvents. Researchers in academic and industrial labs rely on this reagent for applications like alkylation, esterification, and the synthesis of pharmaceutical intermediates.
For educators and students, this reagent provides a practical example of phase-transfer catalysis in organic chemistry experiments. Its stability and predictable behavior make it a preferred choice for teaching advanced synthesis techniques.
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Key Applications
This reagent finds use in multiple laboratory workflows:
In organic synthesis, it acts as a non-nucleophilic base for generating carbanions and enolates. Analytical chemists use it in ion chromatography for the separation of organic acids. The compound is also employed in the preparation of nanoparticles and as a surfactant in certain electrochemical applications.
When handling this chemical, proper laboratory safety protocols should be followed. Always wear appropriate personal protective equipment (PPE) including gloves and goggles. Store the solution in a cool, dry place away from incompatible substances.
Why This Product Stands Out
Merck’s tetrabutylammonium hydroxide solution offers consistent quality with batch-to-batch reliability. The 40% concentration provides optimal reactivity while maintaining ease of handling. Each bottle comes with proper labeling and safety information, ensuring compliance with laboratory standards.
For researchers working on sensitive reactions, the high purity of this reagent minimizes side reactions and improves yield consistency. The 100 ml pack size is ideal for both small-scale experiments and pilot studies.
Safety and Handling
This chemical is corrosive and should be handled with care. In case of skin contact, immediately wash with plenty of water and seek medical attention if irritation persists. Avoid inhalation of vapors and use in a well-ventilated area or fume hood.
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FAQs
What is the concentration of this tetrabutylammonium hydroxide solution?
This product is supplied as a 40% weight/volume solution in water, providing optimal reactivity for most laboratory applications.
Can this reagent be used for phase-transfer catalysis?
Yes, tetrabutylammonium hydroxide is commonly employed as a phase-transfer catalyst due to its solubility in both organic and aqueous phases.
What safety precautions should I take when handling this chemical?
Always wear nitrile gloves, safety goggles, and a lab coat. Work in a fume hood and avoid skin contact or inhalation of vapors.
Is this product suitable for HPLC applications?
While primarily used in synthesis, it can be used in ion chromatography applications with proper method validation.
How should I store this solution?
Store tightly sealed in a cool, dry place away from acids and oxidizing agents. The solution is stable under recommended storage conditions.
