Description
Specifications Table
Product Name – Tetrahydrofuran, HiPerSolv CHROMANORM® for HPLC (unstabilized)
Quantity/Pack Size – 1 L
Form – Liquid
Grade – HPLC
Application – High-performance liquid chromatography (HPLC)
Product Overview
Tetrahydrofuran (THF), HiPerSolv CHROMANORM® for HPLC (unstabilized) is a high-purity solvent specifically designed for demanding high-performance liquid chromatography (HPLC) applications. This unstabilized grade ensures minimal interference with UV detection, making it ideal for sensitive analytical procedures where baseline stability and peak resolution are critical. The HiPerSolv CHROMANORM® certification guarantees consistent quality with extremely low levels of impurities, including water, peroxides, and UV-absorbing compounds. Its low viscosity and excellent solvating power allow for efficient sample dissolution and column performance. The solvent undergoes rigorous quality control to meet strict chromatographic standards, ensuring reliable and reproducible results. Its compatibility with a wide range of HPLC systems and detectors makes it a versatile choice for laboratories requiring high-purity solvents. The unstabilized formulation is particularly suitable for applications where stabilizers could potentially interfere with analysis or react with analytes. Proper storage in tightly sealed containers under inert atmosphere is recommended to maintain its high purity and prevent peroxide formation over time.
FAQs
1. What is the difference between stabilized and unstabilized THF for HPLC?
Unstabilized THF lacks added antioxidants like BHT, which can interfere with certain analytical methods, particularly UV detection. This makes it preferable for applications requiring ultra-low background interference.
2. Can this THF be used with normal-phase HPLC systems?
Yes, its high purity and low water content make it suitable for normal-phase chromatography where polar solvents are required for efficient separation of non-polar compounds.
3. What precautions should be taken when handling unstabilized THF?
Store in a cool, dark place under nitrogen or argon to prevent peroxide formation. Use peroxide test strips periodically and never distill unless peroxide-free is confirmed.
4. Is this THF compatible with LC-MS applications?
While primarily designed for HPLC, its high purity makes it potentially suitable for LC-MS, though volatility and ionization characteristics should be evaluated for specific methods.
5. How does the HiPerSolv CHROMANORM® certification benefit my analysis?
This certification ensures batch-to-batch consistency with documented impurity profiles, providing reliable baseline performance and minimizing method development time.
