Specifications Table

Product Name – Triethyl orthoformate, 98%, anhydrous, AcroSeal® Quantity/Pack Size – 100ML, 800ML Form – Liquid Grade – Anhydrous, 98% Application – Organic synthesis, protecting groups, formylation reactions

Product Overview

Triethyl orthoformate, 98% anhydrous, is a high-purity reagent designed for critical organic synthesis applications where moisture sensitivity is a concern. Packaged under AcroSeal® technology, this reagent ensures long-term stability by minimizing exposure to atmospheric moisture, which can compromise reactivity. The anhydrous grade (98% purity) makes it particularly suitable for formylation reactions, where even trace water can lead to side reactions or reduced yields. Its liquid form allows for easy handling and precise volumetric dosing in laboratory settings. The reagent’s structure, featuring three ethoxy groups bound to a central formyl carbon, enables selective reactivity in esterifications, acetal formations, and as a protecting group in multi-step syntheses. The 100ML and 800ML pack sizes cater to both small-scale experimental needs and larger preparative workflows, while the AcroSeal® packaging preserves integrity during storage and transport. Compatibility with common organic solvents like ethanol, dichloromethane, and THF further enhances its versatility in diverse reaction conditions.

FAQs

1. What is the shelf life of Triethyl orthoformate under AcroSeal® packaging?

The AcroSeal® packaging extends shelf life to 24 months when stored unopened at room temperature, as it prevents moisture ingress that accelerates degradation.

2. Can this reagent be used directly in aqueous reaction mixtures?

No, Triethyl orthoformate hydrolyzes rapidly in water, releasing ethanol and formic acid. It should only be used in anhydrous or low-moisture environments.

3. What are the key storage conditions to maintain its anhydrous state?

Store the sealed bottle in a cool, dry place away from direct sunlight, ideally in a desiccator or under inert gas if opened.

4. Is this product compatible with Lewis acids like BF₃·Et₂O?

Yes, it reacts smoothly with Lewis acids to generate reactive intermediates for formylation, but moisture must be rigorously excluded to avoid side reactions.

5. What alternatives exist if anhydrous grade is unavailable?

Triethyl orthoformate with lower purity (e.g., 95%) can be used but may require pre-drying with molecular sieves or distillation under inert conditions.