Specifications Table

Product Name – Trimethyl orthoformate, 99+%, anhydrous, AcroSeal®
Quantity/Pack Size – 100ML, 800ML
Form – Liquid
Grade – 99% (anhydrous)
Application – Esterification, formylation, protecting group chemistry

Product Overview

Trimethyl orthoformate, 99% anhydrous, is a highly pure reagent designed for critical organic synthesis applications where moisture sensitivity is a concern. Packaged in AcroSeal® bottles, this compound ensures minimal exposure to atmospheric moisture, preserving its reactivity and extending shelf life. Its primary function lies in esterification reactions, where it serves as a mild and selective formylating agent, enabling the synthesis of formate esters under controlled conditions. The anhydrous nature of this reagent makes it particularly valuable in reactions requiring strict exclusion of water, such as the formation of acetals or the protection of carbonyl groups. With a boiling point of 101-103°C and a density of 0.967 g/mL, it offers predictable handling characteristics in laboratory settings. The AcroSeal® packaging further enhances its utility by providing a secure, airtight environment that prevents contamination and degradation over time. This product is compatible with standard glassware and can be stored under inert conditions to maintain its high purity for extended periods.

FAQs

1. What is the shelf life of anhydrous trimethyl orthoformate when stored properly?

When stored in its original AcroSeal® packaging under dry, inert conditions, the reagent maintains its specified purity for at least 12 months from the date of manufacture.

2. Can this reagent be used directly in reactions without further purification?

The 99% anhydrous grade is suitable for most laboratory applications without additional purification, though moisture-sensitive reactions may require handling under nitrogen or argon.

3. What are the key safety precautions for handling this compound?

Use in a well-ventilated fume hood, wear appropriate PPE, and avoid inhalation or skin contact, as it may cause irritation. Store away from ignition sources.

4. Is this product compatible with plastic containers for short-term storage?

While glass is preferred, HDPE or PTFE containers may be used for brief periods, but long-term storage should remain in the original AcroSeal® bottle.

5. How does the AcroSeal® packaging differ from standard bottles?

The AcroSeal® system features a specialized septum and cap design that minimizes air exposure, reducing the risk of moisture absorption during repeated use.