Trt-Cys(Trt)-Oh.Dea 5 G | 8.53118.0005 | Merck

Description

Specifications Table

Product Description

Trt-Cys(Trt)-Oh.Dea is a high-quality protected cysteine derivative widely used in peptide synthesis and biochemical research. This compound features trityl (Trt) protection groups on both the amino and thiol functionalities, ensuring stability during synthesis while allowing selective deprotection when needed. The diethylamine (DEA) salt form enhances solubility, making it ideal for Fmoc-based solid-phase peptide synthesis (SPPS).

Researchers and lab professionals trust this reagent for its consistency and reliability in producing high-purity peptides. Whether you’re working on therapeutic peptide development or structural biology studies, this product delivers the performance you need. Eqipped offers this Merck-manufactured compound with guaranteed authenticity and fast shipping across India.

Need bulk quantities or custom packaging? Contact eqipped for tailored solutions.

The compound’s molecular structure includes:

• Trityl protection on cysteine’s amino group
• Trityl protection on the thiol side chain
• Diethylamine counterion for improved handling

This combination makes it particularly valuable for synthesizing complex peptides where cysteine residues need protection from oxidation or side reactions. The product comes in a 5g pack size, providing sufficient quantity for multiple synthesis runs while maintaining freshness.

Key Applications

This protected cysteine derivative finds applications in:

1. Solid-phase peptide synthesis (SPPS) using Fmoc chemistry

2. Synthesis of cysteine-rich peptides and proteins

3. Bioconjugation chemistry

4. Development of peptide-based therapeutics

5. Structural biology research

The trityl protection groups offer excellent stability under standard SPPS conditions while allowing clean deprotection with mild acid treatment. This balance makes Trt-Cys(Trt)-Oh.Dea a preferred choice among peptide chemists.

Handling and Storage

For optimal performance:

Store at -20°C in a desiccated environment

Avoid exposure to moisture and light

Use in a well-ventilated fume hood

Follow standard laboratory safety protocols

Eqipped ensures proper packaging to maintain product integrity during transit. Each batch undergoes rigorous quality control to meet Merck’s high standards.

Why This Product Stands Out

Several factors make this particular cysteine derivative special:

The dual trityl protection provides exceptional stability during synthesis

The DEA salt form offers better solubility compared to free acid forms

Merck’s manufacturing ensures batch-to-batch consistency

The 5g packaging is ideal for both small-scale research and pilot studies

Looking for related peptide synthesis reagents? Explore eqipped’s full range of protected amino acids.

Safety Information

While this compound is generally safe when handled properly, always:

Wear appropriate personal protective equipment

Avoid skin and eye contact

Do not ingest or inhale

Dispose of according to local regulations

FAQs

What is the purity of Trt-Cys(Trt)-Oh.Dea from Merck?

This product typically has a purity of ≥98% as determined by HPLC, meeting Merck’s stringent quality standards for research chemicals.

Can I use this for Fmoc-based peptide synthesis?

Yes, this compound is specifically designed for Fmoc chemistry and works exceptionally well in standard SPPS protocols.

How should I store this product for long-term use?

For best results, store at -20°C in a desiccator. Proper storage maintains stability for up to 2 years from the date of manufacture.

What’s the difference between Trt and other protecting groups?

Trityl groups offer excellent stability under basic conditions used in Fmoc chemistry while being easily removable with mild acid treatment, making them ideal for cysteine protection.

Does eqipped offer bulk discounts on this product?

Yes, we provide competitive pricing for bulk orders. Contact our sales team for customized quotes based on your requirements.