Description
Specifications Table
| Product Name | X-Phos (2-Dicyclohexylphosphino-2,4,6-Triisopropylbiphenyl) |
|---|---|
| Pack Size | 1 Gms – 5 Gms – 25 Gms |
| Form | Solid |
| Grade | Extrapure, 98% |
| Application | Catalyst in Pd-mediated cross-coupling reactions (Suzuki, Buchwald-Hartwig) |
Product Description
X-Phos, also known as 2-dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl, is a highly effective biphenyl phosphine ligand used in palladium-catalyzed cross-coupling reactions. With a purity of 98%, this extrapure grade ligand is designed for researchers and chemists who demand consistent performance in challenging synthetic applications.
This ligand is particularly valued for its ability to stabilize palladium catalysts, enabling efficient C-C and C-N bond formations. Whether you’re working on Suzuki-Miyaura couplings or Buchwald-Hartwig aminations, X-Phos delivers reliable results with minimal side reactions.
For labs focused on organic synthesis, X-Phos offers a balance of reactivity and selectivity. Its sterically hindered structure prevents unwanted ligand dissociation, ensuring robust catalytic activity even in complex reaction conditions.
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The extrapure grade ensures low impurity levels, making it suitable for sensitive applications where trace contaminants can affect yields. Researchers in academia and industry rely on X-Phos for its reproducibility and compatibility with a wide range of substrates.
When you buy X-Phos online from eqipped, you get a product that meets strict quality standards. Each batch is tested to confirm its purity and performance, so you can focus on your research without worrying about reagent variability.
FAQs
What is X-Phos used for in organic synthesis?
X-Phos is primarily used as a ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig couplings, due to its ability to stabilize the catalyst and improve reaction efficiency.
Is X-Phos air-sensitive?
While X-Phos is relatively stable, it is best stored under inert conditions (e.g., nitrogen or argon) to prevent oxidation over prolonged periods.
What is the typical loading of X-Phos in catalytic reactions?
Most protocols use 1-5 mol% of X-Phos relative to the palladium catalyst, depending on the reaction type and substrate.
Can X-Phos be used in asymmetric synthesis?
Yes, X-Phos has been employed in asymmetric catalytic reactions, though its chiral variants (e.g., chiral phosphines) are often preferred for enantioselective processes.
Where can I buy X-Phos in India?
You can buy X-Phos online from eqipped, a trusted supplier of high-purity lab chemicals for researchers and educators across India.
